​Laughter therapy: A humor-induced hormonal intervention to reduce stress and anxiety

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• Laughter therapy is a universal non-pharmacologic approach to reduce stress and anxiety.

• Therapeutic laughter is a non-invasive, cost-effective, and easily implementable intervention.

• Laughter therapy can be used during COVID-19 pandemic as a useful supplementary therapy to reduce the mental health burden.

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The Effect of Laughter Therapy on Physical and Mental Health: Systematic Review

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As a result of the studies conducted, laughter therapy has positive effects in reducing depression, reducing stress and anxiety, increasing sleep quality, reducing pain, and

increasing physical functions in individuals of different age groups and health conditions.

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Effects of laughter therapy on depression and anxiety: A dose-response meta-analysis with trial sequential analysis

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Laughter therapy effectively reduces depression, anxiety, and stress.

• Dose-response meta-analysis identifies optimal therapy durations of 400–600 min.

• Subgroup analysis supports benefits across diverse ages, conditions, and care settings.

• Study strengthens evidence for integrating laughter therapy into mental health care.

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